A Patient with Henoch-Schönlein Purpura with Intussusception and intractable Nephritis

Henoch-Schönlein purpura nephritis.

Henoch-Schönlein purpura (HSP) is a systemic vasculitic disorder first reported by Heberden in 1806. The association of purpura and joint pain was described by Schönlein in 1837, who termed it “peliosis rheumatica.” Henoch added a description of four children with skin lesions associated with colicky abdominal pain, gastrointestinal hemorrhage, and joint pain in 1874, and in 1899 pointed out th...

A Patient with Henoch-Schönlein Purpura with Intussusception and intractable Nephritis

Henoch-Schönlein purpura (HSP) is the most common vasculitis in children, mainly affecting the small vessels of the skin, joints, gastrointestinal tract, and kidneys. Although most cases of HSP resolve spontaneously without sequelae, serious nephrological and intestinal problems may occur in some cases. We experienced a case of HSP complicated by simultaneous intussusception and nephritis in a ...

Chapter 11: Henoch-Schönlein purpura nephritis

11.1: Treatment of HSP nephritis in children 11.1.1: We suggest that children with HSP nephritis and persistent proteinuria, 40.5-1 g/d per 1.73 m, are treated with ACE-I or ARBs. (2D) 11.1.2: We suggest that children with persistent proteinuria, 41 g/d per 1.73 m, after a trial of ACE-I or ARBs, and GFR 450 ml/min per 1.73 m, be treated the same as for IgAN with a 6-month course of corticoster...

Azathioprine treatment in two children with Henoch–Schönlein purpura nephritis

A patient with Henoch-Schönlein purpura and intra-alveolar haemorrhage

Henoch-Schönlein purpura (HSP) is a systemic vasculitis predominantly occurring in prepubertal children and characterised by a purpuric rash on the lower extremities, arthralgia and abdominal pain. Renal involvement is not uncommon affecting between 20 and 80% of patients [1] and severe nephrotic syndrome or nephritis is frequently associated with significant renal disease, morbidity and mortal...